منابع مشابه
Putting together rather than taking apart.
The town of Ascona in Switzerland, nestled on the northern shore of Lago Maggiore, hosted the 112 participants in the first systems biology meeting focused on developmental biology. The EMBO workshop was held between 16 and 20 August and brought together a multidisciplinary group of scientists who use systems approaches to understand how the size and shape of multicellular organisms and organs ...
متن کاملArms together, CENs apart
putative calcium channel specific to sperm tails may be the best target yet for a male contraceptive. The protein, dubbed CatSper, was discovered in a homology search by David Clapham and colleagues of Harvard Medical School, Boston, MA. CatSper looks like a calcium channel, although Clapham could not detect a calcium current in transfected cells, probably because another component of the chann...
متن کاملSignaling together apart
Dormant tumors awaken hat happens during tumor remission? After chemotherapy, tumor cell numbers may be reduced, or surviving cells may enter an altered, dormant state. Evidence for dormancy now comes from Catherine Shachaf, Dean Felsher (Stanford University, Stanford, CA), and colleagues. In their mouse model, liver tumors can be forced into dormancy and then reawakened at will. As in previous...
متن کاملPutting Humpty together and pulling him apart: Accessing and unbinding the hippocampal item-context engram
A remarkable act of memory entails binding different forms of information. We focus on the timeless question of how the bound engram is accessed such that its component features-item and context-are extracted. To shed light on this question, we investigate the dynamics between brain structures that together mediate the binding and extraction of item and context. Converging evidence has implicat...
متن کاملPutting it all together.
• Let's look at some relatively simple privileged programs • How do they combine the different mechanisms we've seen? • What are the threats? The defenses?
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2010
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2010.183